Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28967629 | 0.80 | PDE3B (0.53) | LTA4HPDE3BPDE3AALDH1A1KDM4E | |
| SCHEMBL16114401 | 0.74 | LMNA (0.75) | LMNATDP1CYP19A1HTTLTA4H | |
| SCHEMBL30535283 | 0.74 | LMNA (0.82) | LMNATDP1CYP19A1HTTLTA4H | |
| SCHEMBL676142 | 0.74 | LMNA (0.82) | LMNATDP1CYP19A1HTTLTA4H | |
| SCHEMBL2540132 | 0.74 | LMNA (0.59) | LMNATDP1CYP19A1HTTLTA4H | |
| SCHEMBL17423777 | 0.74 | LMNA (0.59) | LMNATDP1CYP19A1HTTLTA4H | |
| SCHEMBL30832786 | 0.73 | PDE3B (0.65) | CYP19A1PDE3BPDE3ACYP11B1CYP11B2 | |
| SCHEMBL1884345 | 0.73 | PDE3B (0.65) | CYP19A1PDE3BPDE3ACYP11B1CYP11B2 | |
| SCHEMBL17423783 | 0.73 | FGFR1 (0.57) | LMNATDP1CYP19A1HTTLTA4H | |
| SCHEMBL17423781 | 0.72 | LMNA (0.53) | LMNATDP1CYP19A1HTTLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768761-B | Novel benzimidazole derivatives | 卡尔那生物科学株式会社 | 2025-02-25 | — | — | CN | disclosed |
| US-20240279205-A1 | NOVEL BENZIMIDAZOLE DERIVATIVE | CARNA BIOSCIENCES, INC. (JP) | 2024-08-22 | — | — | US | disclosed |
| CN-115768761-A | Novel benzimidazole derivatives | 卡尔那生物科学株式会社 | 2023-03-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279205-A1 | NOVEL BENZIMIDAZOLE DERIVATIVE | STING1, IRF3, TBK1 | LMNA 3295/4885TDP1 414/4885CYP19A1 2322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.