Dl-Phenylalanine

Dl-Phenylalanine

SCHEMBL28967804

NC(Cc1ccccc1)C(=O)O.O=[N+]([O-])c1ccc(-c2cnon2)cc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.48
ALPI P09923 1/20 0.48
PTGS1 P23219 1/20 0.48
XIAP P98170 1/20 0.48
SLC7A5 Q01650 1/20 0.48
MMP2 P08253 1/20 0.45
MC4R P32245 1/20 0.43
TPH1 P17752 5/20 0.43
ANPEP P15144 1/20 0.41
ERAP2 Q6P179 1/20 0.41
ERAP1 Q9NZ08 1/20 0.41
NPC1 O15118 1/20 0.41
TP53 P04637 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
FAAH O00519 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL326687 0.78 RAB9A (0.47) PKMNPC1RAB9AMEN1KMT2A
Dl-Phenylalanine SCHEMBL5582272 0.77 SLC7A5 (0.63) PKMALPIPTGS1XIAPSLC7A5
Phenylalanine SCHEMBL2544094 0.77 SLC7A5 (0.63) PKMALPIPTGS1XIAPSLC7A5
SCHEMBL26443 0.77 SLC7A5 (0.61) PKMALPIPTGS1XIAPSLC7A5
SCHEMBL437181 0.77 SLC7A5 (0.61) PKMALPIPTGS1XIAPSLC7A5
SCHEMBL503312 0.77 SLC7A5 (0.61) PKMALPIPTGS1XIAPSLC7A5
SCHEMBL26444 0.77 SLC7A5 (0.61) PKMALPIPTGS1XIAPSLC7A5
Phenylalanine SCHEMBL10903052 0.76 SLC7A5 (0.61) PKMALPIPTGS1XIAPSLC7A5
Dl-Phenylalanine SCHEMBL27740947 0.76 SLC7A5 (0.61) PKMALPIPTGS1XIAPSLC7A5
Water SCHEMBL4754409 0.75 SLC7A5 (0.59) PKMALPIPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115806583-A Amphiphilic polypeptide derivative and application thereof 中国药科大学 2023-03-17 CN disclosed