Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559241 | 0.82 | ALDH1A1 (0.50) | LMNAALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL11615405 | 0.70 | CTRC (0.46) | ALDH1A1TSHR | |
| SCHEMBL2235887 | 0.70 | ALDH1A1 (0.54) | LMNAALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL13585322 | 0.70 | ALDH1A1 (0.54) | LMNAALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL11121354 | 0.69 | ALDH1A1 (0.53) | LMNAALDH1A1TP53KDM4EPKM | |
| Acetic Acid SCHEMBL27263112 | 0.68 | LMNA (0.53) | LMNAALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL6564813 | 0.67 | TDP1 (0.56) | LMNAALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL8349568 | 0.66 | ALDH1A1 (0.79) | LMNAALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL6568086 | 0.66 | ALDH1A1 (0.61) | LMNAALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL8006814 | 0.66 | MMP9 (0.65) | LMNAALDH1A1KDM4EPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666560-A | Methods and pharmaceutical compositions for treating thromboxane A2 receptor antagonists of COVID-19 | 马丁·奥格特树 | 2023-01-31 | — | — | CN | disclosed |