Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15822146 | 0.81 | BACE1 (0.45) | PGRPAX8PTPN5 | |
| SCHEMBL1467472 | 0.79 | — | — | |
| SCHEMBL30104097 | 0.78 | PGR (0.44) | PGR | |
| SCHEMBL30112130 | 0.78 | RORC (0.44) | CA1CA2PGRARCYP11B2 | |
| SCHEMBL30112093 | 0.78 | EGLN2 (0.39) | PGRARCYP11B2 | |
| SCHEMBL6057498 | 0.77 | PGR (0.43) | PGRKIF11 | |
| SCHEMBL28972415 | 0.77 | MMP3 (0.39) | MMP3GAAKIF11HDAC2MMP2 | |
| SCHEMBL30112085 | 0.76 | CTSA (0.39) | PGR | |
| SCHEMBL30112097 | 0.76 | CYP11B2 (0.46) | PGRARCYP11B2 | |
| SCHEMBL30112094 | 0.76 | CYP11B2 (0.47) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016011-B | Amide derivative and medical use thereof | 北京美倍他药物研究有限公司 | 2023-02-03 | — | — | CN | disclosed |