Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2753720 | 0.85 | HSD11B1 (0.42) | HSD11B1PSMB8NOTUMSCN9AMPL | |
| SCHEMBL2752028 | 0.81 | MPL (0.33) | NOTUMALDH1A1TRPA1MPL | |
| SCHEMBL2749974 | 0.79 | CES2 (0.37) | SCN9AMPL | |
| SCHEMBL2750143 | 0.79 | CES2 (0.37) | HSD11B1SCN9AMPL | |
| SCHEMBL2894960 | 0.78 | HSD11B1 (0.39) | HSD11B1SCN9A | |
| SCHEMBL2902960 | 0.76 | TRPV1 (0.36) | ALDH1A1TRPV1 | |
| SCHEMBL2897688 | 0.76 | DHODH (0.33) | — | |
| SCHEMBL577973 | 0.73 | ALDH1A1 (0.46) | HSD11B1NOTUMALDH1A1HPGD | |
| SCHEMBL2903265 | 0.72 | TRPA1 (0.34) | TRPA1 | |
| SCHEMBL2752090 | 0.71 | NOTUM (0.41) | NOTUMMPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |
| EP-0556123-A1 | Pyrethrinoid esters of thiazolylalcohols, process for their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | HSD11B1 4143/4885PSMB8 3188/4885NOTUM 945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.