Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | PDE1A | P54750 | 4/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30272736 | 0.80 | ROCK2 (0.52) | ROCK2AGTR1AGTR2ALDH1A1L3MBTL1 | |
| SCHEMBL30272726 | 0.79 | ROCK2 (0.46) | ROCK2PDE1BLMNAALDH1A1L3MBTL1 | |
| SCHEMBL28976779 | 0.73 | ROCK2 (0.68) | ROCK2AGTR1AGTR2LMNAADORA3 | |
| SCHEMBL2494040 | 0.68 | LMNA (0.61) | LMNAALDH1A1L3MBTL1CACNA1GCACNA1H | |
| SCHEMBL8231635 | 0.67 | SIGMAR1 (0.58) | — | |
| SCHEMBL28976775 | 0.67 | ALDH1A1 (0.45) | ROCK2PDE1BKCNH2LMNAALDH1A1 | |
| SCHEMBL30928893 | 0.66 | PDE1A (0.42) | PDE1BALDH1A1L3MBTL1PDE1APDE1C | |
| SCHEMBL30928923 | 0.65 | PDE4A (0.53) | LMNAALDH1A1ADORA3ADORA2APDE4A | |
| SCHEMBL31429308 | 0.65 | HTR4 (0.48) | ROCK2 | |
| SCHEMBL15882181 | 0.65 | HTR4 (0.48) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703761-A | Compound as WWP1 inhibitor and application thereof | 首药控股(北京)股份有限公司 | 2023-02-17 | — | — | CN | disclosed |