Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897661 | 0.85 | EPHX2 (0.35) | EPHX2CYP17A1GAAHSD11B1TRPV1 | |
| SCHEMBL2893944 | 0.85 | TRPA1 (0.41) | EPHX2CYP17A1HSD11B1TRPV1 | |
| SCHEMBL16927647 | 0.79 | CYP1A2 (0.47) | GAAHSD11B1MAPTHTT | |
| SCHEMBL2903040 | 0.79 | CYP17A1 (0.35) | EPHX2CYP17A1HSD11B1TRPV1 | |
| SCHEMBL2893959 | 0.79 | ALDH1A1 (0.42) | HSD11B1TRPV1MAPTHTT | |
| SCHEMBL2902281 | 0.78 | OXTR (0.31) | — | |
| SCHEMBL2900240 | 0.76 | EPHX2 (0.40) | EPHX2CYP17A1GAAHSD11B1TRPV1 | |
| SCHEMBL1304709 | 0.76 | OXTR (0.46) | CYP17A1GAATRPV1HTT | |
| SCHEMBL2896799 | 0.76 | EPHX2 (0.39) | EPHX2CYP17A1GAAHSD11B1TRPV1 | |
| SCHEMBL2902790 | 0.74 | CYP17A1 (0.39) | CYP17A1GAAHSD11B1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | EPHX2 2167/4885CYP17A1 4454/4885GAA 2373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.