Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 4/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SLC11A2 | P49281 | 2/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2902281 | 0.80 | OXTR (0.31) | OXTRAVPR1A | |
| SCHEMBL2897752 | 0.76 | EPHX2 (0.47) | GAATRPV1HTTCYP17A1 | |
| SCHEMBL219809 | 0.76 | SMN1; SMN2 (0.41) | RAB9AKDM4EGAAHTTSMN1; SMN2 | |
| SCHEMBL15015880 | 0.75 | HTR3E (0.36) | RAB9AKMT2A | |
| SCHEMBL15016120 | 0.75 | KMT2A (0.33) | RAB9ASMN1; SMN2ACHEKMT2A | |
| SCHEMBL1303649 | 0.74 | RAB9A (0.38) | OXTRAVPR1ARAB9ACYP17A1SMN1; SMN2 | |
| SCHEMBL2897661 | 0.74 | EPHX2 (0.35) | KDM4EGAATRPV1CYP17A1KMT2A | |
| SCHEMBL2903040 | 0.74 | CYP17A1 (0.35) | TRPV1CYP17A1 | |
| SCHEMBL2893944 | 0.74 | TRPA1 (0.41) | TRPV1CYP17A1 | |
| SCHEMBL2893959 | 0.73 | ALDH1A1 (0.42) | KDM4ETRPV1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342196-B1 | PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2015-07-29 | — | — | EP | disclosed |
| US-8729083-B2 | Pyrazole compounds for controlling invertebrate pests | BASF SE (DE) | 2014-05-20 | — | — | US | disclosed |
| US-20110269770-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | BASF SE (DE) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269770-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | GRIN2C, GRIN2D, NR2C2 | OXTR 344/4885AVPR1A 231/4885PDCD1 4411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.