Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5919390 | 0.89 | PRKCZ (0.47) | PRKCZHTTTP53ALDH1A1KDM4E | |
| SCHEMBL2897758 | 0.89 | LMNA (0.47) | PRKCZHTTTP53PTPN1ALDH1A1 | |
| SCHEMBL5919158 | 0.87 | PRKAB2 (0.58) | PRKCZHTTTP53ALDH1A1KDM4E | |
| SCHEMBL3611853 | 0.83 | PRKAB2 (0.47) | PRKCZTP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL4155315 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTKDM5AKDM5B | |
| SCHEMBL4509757 | 0.77 | PRKCZ (0.56) | PRKCZHTTTP53PTPN1ALDH1A1 | |
| SCHEMBL688813 | 0.74 | ALDH1A1 (0.62) | PRKCZTP53ALDH1A1KDM4EPOLB | |
| SCHEMBL1189947 | 0.73 | GSK3B (0.53) | TP53PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1191503 | 0.73 | GSK3B (0.53) | TP53PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1189879 | 0.73 | PRKAB2 (0.47) | ALDH1A1HPGDPRKAB2PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879899-B1 | THIENOPYRIDINE DERIVATIVES AS POTASSIUM CHANNEL INHIBITORS | XENTION LTD (GB) | 2010-08-04 | — | — | EP | disclosed |