Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897758 | 0.82 | LMNA (0.47) | ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL2897779 | 0.80 | PRKCZ (0.57) | ALDH1A1KDM4EKDM5AKDM5BMAPT | |
| SCHEMBL5919390 | 0.80 | PRKCZ (0.47) | ALDH1A1KDM4EKDM5AKDM5BMAPT | |
| SCHEMBL4518265 | 0.78 | KDM5A (0.52) | ALDH1A1LMNAKDM4EKDM5AKDM5B | |
| SCHEMBL26252901 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4EKDM5AKDM5B | |
| SCHEMBL5919158 | 0.78 | PRKAB2 (0.58) | ALDH1A1LMNAKDM4EKDM5AKDM5B | |
| SCHEMBL4158514 | 0.76 | KDM5A (0.55) | ALDH1A1LMNAKDM4EKDM5AKDM5B | |
| SCHEMBL4144587 | 0.75 | EGLN1 (0.40) | ALDH1A1KDM4EERCC5FEN1 | |
| SCHEMBL8108086 | 0.73 | ALDH1A1 (0.47) | ALDH1A1KDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL321963 | 0.72 | KDM5A (0.54) | ALDH1A1LMNAKDM4EKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176825-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION | 2009-07-09 | — | — | US | disclosed |
| US-7553849-B2 | Compounds | ACTIVE BIOTECH AB (SE) | 2009-06-30 | — | — | US | disclosed |
| EP-1776369-B1 | THIENOPYRIDONE CARBOXAMIDES AND THEIR MEDICAL USE | ACTIVE BIOTECH AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| US-20060004038-A1 | Novel compounds | ACTIVE BIOTECH AB (SE) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004038-A1 | Novel compounds | REL, CLIC4, C5 | ALDH1A1 3955/4885LMNA 4599/4885KDM4E 1493/4885 |
| US-20090176825-A1 | PROLYL HYDROXYLASE INHIBITORS | HIF1AN, EGLN2, EGLN3 | ALDH1A1 319/4885LMNA 3318/4885KDM4E 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.