Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gamma-Aminobutyric Acid SCHEMBL2897912 | 0.76 | KMT2A (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6135895 | 0.72 | NPC1 (0.33) | SMN1; SMN2 | |
| Phthalic Anhydride SCHEMBL10455461 | 0.71 | HDAC3 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Aminocaproic Acid SCHEMBL379308 | 0.71 | ALDH1A1 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Gamma-Aminobutyric Acid SCHEMBL28119738 | 0.69 | HDAC3 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Gamma-Aminobutyric Acid SCHEMBL27860343 | 0.68 | LMNA (0.88) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Gamma-Aminobutyric Acid SCHEMBL29221604 | 0.67 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Biphenyl SCHEMBL29081077 | 0.66 | FFAR1 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Gamma-Aminobutyric Acid SCHEMBL3017607 | 0.66 | LMNA (0.83) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL17512909 | 0.65 | USP1 (0.37) | LMNAGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160082105-A1 | Antibody Buffering of a Ligand in Vivo | ARROWSMITH TECHNOLOGIES CORPORATION | 2016-03-24 | — | — | US | disclosed |
| US-9173958-B2 | Antibody buffering of a ligand in vivo | ARROWSMITH TECHNOLOGIES CORPORATION (US) | 2015-11-03 | — | — | US | disclosed |
| WO-2006036568-A9 | ANTIBODY BUFFERING OF A LIGAND IN VIVO | ARROWSMITH TECHNOLOGIES LLP (US) | 2006-07-27 | — | — | WO | disclosed |
| US-20060062778-A1 | Antibody buffering of a ligand in vivo | ARROWSMITH TECHNOLOGIES CORPORATION | 2006-03-23 | — | — | US | disclosed |