SCHEMBL28979280

SCHEMBL28979280

CCC(c1ccccc1)C(c1ccccc1)C(C#N)C#N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.44
HKDC1 Q2TB90 1/20 0.43
ESR1 P03372 2/20 0.42
ESR2 Q92731 1/20 0.42
LMNA P02545 4/20 0.39
TSHR P16473 1/20 0.39
ALDH1A1 P00352 5/20 0.38
HPGD P15428 4/20 0.38
TAAR1 Q96RJ0 1/20 0.37
MIF P14174 1/20 0.37
MAPT P10636 2/20 0.35
SLC6A2 P23975 2/20 0.35
SLC6A3 Q01959 2/20 0.35
CYP1A2 P05177 1/20 0.35
PGR P06401 1/20 0.35
CHRM2 P08172 1/20 0.35
CYP3A4 P08684 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
AR P10275 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24849087 0.86 TRPA1 (0.48) TRPA1HKDC1ESR1ESR2LMNA
SCHEMBL29001551 0.83 TRPA1 (0.39) TRPA1LMNATSHRALDH1A1HPGD
SCHEMBL11206738 0.82 HKDC1 (0.53) TRPA1HKDC1ESR1LMNATAAR1
SCHEMBL30306987 0.80 OPRM1 (0.39) TRPA1ALDH1A1HPGDOPRM1
SCHEMBL1344286 0.77 ESR1 (0.68) TRPA1HKDC1ESR1ESR2LMNA
SCHEMBL29054038 0.76 ALDH1A1 (0.40) TRPA1LMNATSHRALDH1A1HPGD
SCHEMBL29054028 0.76 TRPA1 (0.45) TRPA1LMNATSHRALDH1A1HPGD
SCHEMBL4071581 0.75 HKDC1 (0.65) TRPA1HKDC1ESR1LMNATAAR1
SCHEMBL30307009 0.75 TRPA1 (0.43) TRPA1ESR1ESR2LMNATSHR
SCHEMBL27704927 0.75 TRPA1 (0.48) TRPA1ESR1ESR2LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115710199-B Photooxidation reduction catalytic process 深圳湾实验室坪山生物医药研发转化中心 2024-06-28 CN disclosed
CN-115710199-A Photo-oxidation-reduction catalysis method 深圳湾实验室坪山生物医药研发转化中心 2023-02-24 CN disclosed
CN-113387837-B Photo-oxidation-reduction catalysis method 深圳湾实验室坪山生物医药研发转化中心 2023-02-21 CN disclosed
CN-113387837-A Photo-oxidation-reduction catalysis method 深圳湾实验室坪山生物医药研发转化中心 2021-09-14 CN disclosed