Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.40 |
| ▸ | NPC1 | O15118 | 9/20 | 0.40 |
| ▸ | RAB9A | P51151 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | MEN1 | O00255 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22431061 | 0.74 | — | — | |
| SCHEMBL13628700 | 0.73 | ALOX5 (0.36) | CYP1A2CYP2C9CYP2C19PTGS1PTGS2 | |
| SCHEMBL11983825 | 0.68 | NPC1 (0.46) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL24502044 | 0.67 | — | — | |
| SCHEMBL15827302 | 0.66 | NPC1 (0.45) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL101638 | 0.65 | — | — | |
| SCHEMBL24501679 | 0.64 | — | — | |
| SCHEMBL17811141 | 0.63 | NPC1 (0.40) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL13411813 | 0.63 | ADH5 (0.36) | — | |
| SCHEMBL22206279 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286211-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES LIMITED (IN) | 2010-11-11 | — | — | US | disclosed |
| US-7572753-B2 | Tetrazole fungicides | CHEMTURA CORPORATION (US) | 2009-08-11 | — | — | US | disclosed |
| EP-1799677-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | Ranbaxy Laboratories Limited (IN) | 2007-06-27 | — | — | EP | disclosed |
| US-20070060631-A1 | 2-cyanomethyl-5-(3-substituted phenyl or 5-substituted thien-2-yl)-2H-tetrazoles; agricultural fungicides such as for rice blast | CROMPTON COLORS INCORPORATED | 2007-03-15 | — | — | US | disclosed |
| WO-2006038100-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES LIMITED (IN) | 2006-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286211-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | OXA1L, PDK4, MLYCD | SMN1; SMN2 3845/4885NPC1 3916/4885RAB9A 4328/4885 |
| US-20070060631-A1 | 2-cyanomethyl-5-(3-substituted phenyl or 5-substituted thien-2-yl)-2H-tetrazoles; agricultural fungicides such as for rice blast | TH, HAO2, TDO2 | SMN1; SMN2 4312/4885NPC1 3648/4885RAB9A 3177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.