SCHEMBL28985271

SCHEMBL28985271

COC(c1ccc(-c2ccc(C=C(F)F)cc2)cc1)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LIPE Q05469 2/20 0.31
NQO2 P16083 1/20 0.31
PTGS1 P23219 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28933462 0.77 ESR1 (0.31)
SCHEMBL28985000 0.76 KIF11 (0.42)
SCHEMBL12199531 0.75 TYR (0.48) LIPE
SCHEMBL28985017 0.75 KIF11 (0.45)
SCHEMBL19056940 0.73 TP53 (0.43)
SCHEMBL28985020 0.72 KIF11 (0.44)
SCHEMBL28985275 0.72 CTSL (0.38) LIPE
SCHEMBL9626484 0.71 ALDH1A1 (0.55) NQO2PTGS1
SCHEMBL12282035 0.70 CHRNA7 (0.37) LIPE
SCHEMBL12282257 0.70 AOC3 (0.42) LIPE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115948752-A Reaction method for selective fluorination functionalization of harmonious difluoro olefin 暨南大学 2023-04-11 CN disclosed