Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 7/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21616740 | 0.76 | HCAR2 (0.43) | LMNAKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL28476138 | 0.74 | MAPK1 (0.41) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30340445 | 0.74 | SIRT6 (0.41) | LMNACDK8CDK19ATMPRKCE | |
| SCHEMBL25652309 | 0.74 | LMNA (0.44) | LMNAKDM4EALDH1A1HPGDGAA | |
| SCHEMBL2610401 | 0.74 | LMNA (0.41) | LMNAKDM4EALDH1A1HPGDGAA | |
| SCHEMBL21222762 | 0.74 | LMNA (0.41) | LMNAKDM4EALDH1A1HPGDGAA | |
| SCHEMBL14685854 | 0.73 | LMNA (0.47) | LMNAKDM4EALDH1A1HPGDGAA | |
| SCHEMBL30703767 | 0.70 | LMNA (0.38) | LMNAKDM4EALDH1A1HPGDGAA | |
| SCHEMBL16647331 | 0.68 | LMNA (0.42) | LMNAKDM4EALDH1A1HPGDGAA | |
| SCHEMBL7618495 | 0.66 | RXRA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886219-B | Immunosuppressant, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2023-04-25 | — | — | CN | disclosed |