Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1320478 | 0.83 | L3MBTL1 (0.50) | G6PDCASP7CASP6KDM4EHTT | |
| SCHEMBL24009070 | 0.82 | ALDH1A1 (0.49) | KDM4EHTTALDH1A1KMT2AHPGD | |
| SCHEMBL6426977 | 0.82 | ALDH1A1 (0.65) | KDM4EHTTALDH1A1KMT2APTK2B | |
| SCHEMBL18700982 | 0.81 | FABP3 (0.50) | KDM4EHTTALDH1A1KMT2APTK2B | |
| SCHEMBL28259939 | 0.80 | ALDH1A1 (0.62) | KDM4EHTTALDH1A1KMT2APTK2B | |
| SCHEMBL9352062 | 0.80 | PTGER1 (0.59) | KDM4EHTTALDH1A1MAPK1TDP1 | |
| SCHEMBL9348401 | 0.80 | G6PD (0.47) | G6PDCASP7CASP6KDM4EHTT | |
| SCHEMBL7773567 | 0.80 | KMT2A (0.50) | G6PDCASP7CASP6KDM4EHTT | |
| SCHEMBL7716207 | 0.80 | G6PD (0.59) | G6PDCASP7CASP6KDM4EHTT | |
| SCHEMBL30314458 | 0.80 | G6PD (0.59) | G6PDCASP7CASP6KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996912-A | Iminothiolanone inhibitors of ENPP1 | 沃拉斯查疗法公司 | 2023-04-21 | — | — | CN | disclosed |