Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28987832 | 0.88 | GHSR (0.51) | GHSRKIF11HTTMAPTMEN1 | |
| SCHEMBL28987815 | 0.84 | MAPT (0.51) | EGFRKIF11HTTMAPTKMT2A | |
| SCHEMBL10082865 | 0.77 | RAB9A (0.57) | HTTMAPTKDM4ECYP3A4POLB | |
| SCHEMBL14572843 | 0.77 | KIF11 (0.46) | KIF11HTTMAPTMEN1KMT2A | |
| SCHEMBL7409293 | 0.76 | PARP1 (0.45) | CDK2EGFRGHSRMAPTMEN1 | |
| SCHEMBL28987825 | 0.74 | MAPT (0.68) | KIF11HTTMAPTMEN1KMT2A | |
| SCHEMBL14572845 | 0.73 | KIF11 (0.45) | KIF11MAPTMEN1KMT2AKDM4E | |
| SCHEMBL6330362 | 0.72 | OXER1 (0.56) | MAPTMEN1KMT2AKDM4ECYP3A4 | |
| SCHEMBL19481419 | 0.72 | AHR (0.52) | CDK2EGFRKIF11CCNB2CDK1 | |
| SCHEMBL28987833 | 0.72 | SIRT1 (0.60) | HTTMAPTKDM4ECYP3A4SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835622-A | N-tert-butyl protection-3-substituted indole compound and preparation method thereof | 常州大学 | 2022-08-02 | — | — | CN | disclosed |