Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27743375 | 0.74 | POLB (0.40) | HTR1ASLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL2913724 | 0.73 | POLB (0.42) | SLC6A2ADRA1AHTR2BSLC6A3CHRNA7 | |
| SCHEMBL10349667 | 0.71 | PRCP (0.41) | HTR1ASLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL7215003 | 0.71 | HRH3 (0.38) | HTR1ASLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL2915821 | 0.71 | ADRB1 (0.40) | ALDH1A1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10383318 | 0.70 | HRH3 (0.37) | HTR1ASLC6A2ADRA1AHTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL10382641 | 0.70 | PRCP (0.40) | HTR1ASLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL2908423 | 0.70 | KMT2A (0.40) | ALDH1A1TDP1SLC18A3SIGMAR1TSHR | |
| SCHEMBL7072099 | 0.69 | CHRNB2 (0.44) | HTR1ASLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL2908098 | 0.69 | KDM1A (0.37) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996908-A | Antagonists of GPR39 proteins | 俄勒冈健康科学大学 | 2023-04-21 | — | — | CN | disclosed |