Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28989534 | 0.81 | HSP90AB1 (0.44) | LMNAUSP2MAPTALDH1A1KDM4E | |
| SCHEMBL2021817 | 0.78 | LMNA (0.41) | LMNAADORA2AADORA1MAPTALDH1A1 | |
| SCHEMBL2027503 | 0.76 | SORD (0.45) | LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL2021947 | 0.76 | CYP1A2 (0.44) | MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL15317599 | 0.75 | ALDH1A1 (0.43) | LMNAUSP2MAPTALDH1A1KDM4E | |
| SCHEMBL21157766 | 0.75 | CRHBP (0.42) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL3242401 | 0.73 | CYP1A2 (0.37) | LMNAMAPTALDH1A1GBA1KMT2A | |
| SCHEMBL3716189 | 0.73 | LMNA (0.46) | LMNAUSP2ALDH1A1KDM4EGBA1 | |
| SCHEMBL28989611 | 0.73 | LMNA (0.41) | LMNAALDH1A1GBA1KMT2AHPGD | |
| SCHEMBL15317600 | 0.73 | CYP2C19 (0.49) | ADORA2AADORA1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996932-A | New macrocyclic LRRK2 kinase inhibitors | 法国施维雅药厂 | 2023-04-21 | — | — | CN | disclosed |