Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28989708

CO[Si](CCCc1cccc2sc(-c3nc4ccccc4s3)nc12)(OC)OC.S.S.S.S

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 10/20 0.45
RAB9A P51151 10/20 0.45
MAPT P10636 7/20 0.45
TDP1 Q9NUW8 3/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
KDM4E B2RXH2 8/20 0.45
NPC1 O15118 6/20 0.45
PKM P14618 3/20 0.45
ALDH1A1 P00352 8/20 0.44
KMT2A Q03164 6/20 0.44
MEN1 O00255 5/20 0.44
HPGD P15428 4/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
GAA P10253 4/20 0.43
HCRTR1 O43613 2/20 0.43
GLA P06280 2/20 0.43
PTGS2 P35354 1/20 0.41
PPARG P37231 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8826550 0.81 SMN1; SMN2 (0.42) SMN1; SMN2RAB9AMAPTTDP1NFKB1
SCHEMBL8826755 0.80 SMN1; SMN2 (0.40) SMN1; SMN2RAB9AMAPTTDP1NFKB1
SCHEMBL8826672 0.80 SMN1; SMN2 (0.40) SMN1; SMN2RAB9AMAPTTDP1NFKB1
SCHEMBL8826837 0.79 SMN1; SMN2 (0.40) SMN1; SMN2RAB9AMAPTTDP1NFKB1
SCHEMBL8826664 0.79 SMN1; SMN2 (0.40) SMN1; SMN2RAB9AMAPTTDP1NFKB1
Hydrogen Sulfide SCHEMBL467041 0.78 SMN1; SMN2 (0.54) SMN1; SMN2RAB9AMAPTNPC1PKM
SCHEMBL11324676 0.77 PTGS2 (0.39) SMN1; SMN2RAB9AMAPTTDP1NFKB1
SCHEMBL6911656 0.76 SMN1; SMN2 (0.55) SMN1; SMN2RAB9AMAPTNPC1PKM
SCHEMBL8826759 0.75 ILK (0.41) SMN1; SMN2RAB9AMAPTTDP1NFKB1
SCHEMBL329562 0.75 PTGS2 (0.38) MAPTTDP1KDM4EALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111902442-B Resin composition, secondary coating material for optical fiber, and optical fiber 住友电气工业株式会社 2023-04-04 CN disclosed
CN-115668021-A Resin composition, secondary coating material for optical fiber, and method for producing optical fiber 住友电气工业株式会社 2023-01-31 CN disclosed
CN-115190981-A Optical fiber ribbon and optical fiber cable 住友电气工业株式会社 2022-10-14 CN disclosed