SCHEMBL329562

SCHEMBL329562

CO[Si](CCCc1cccc2sc(SSSSc3nc4c(CCC[Si](OC)(OC)OC)cccc4s3)nc12)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.38
ALDH1A1 P00352 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
CYP3A4 P08684 1/20 0.34
PDK1 Q15118 2/20 0.33
FBP1 P09467 2/20 0.33
ADRA2A P08913 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
DRD2 P14416 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
DRD1 P21728 1/20 0.33
MC5R P33032 1/20 0.33
OPRM1 P35372 1/20 0.33
DRD3 P35462 1/20 0.33
OPRK1 P41145 1/20 0.33
CCR2 P41597 1/20 0.33
HTR6 P50406 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11324676 0.90 PTGS2 (0.39) PTGS2ALDH1A1TDP1CYP3A4HPGD
SCHEMBL330194 0.89 PTGS2 (0.35) PTGS2ALDH1A1TDP1CYP3A4PDK1
SCHEMBL466830 0.88 FBP1 (0.37) PTGS2ALDH1A1TDP1PDK1FBP1
SCHEMBL28492615 0.83 PTGS2 (0.35) PTGS2ALDH1A1FBP1
SCHEMBL8826660 0.81 FBP1 (0.46) PTGS2ALDH1A1TDP1CYP3A4PDK1
SCHEMBL8826831 0.80 FBP1 (0.45) PTGS2ALDH1A1TDP1CYP3A4PDK1
SCHEMBL8827097 0.80 FBP1 (0.45) PTGS2ALDH1A1TDP1CYP3A4PDK1
SCHEMBL8827126 0.80 FBP1 (0.45) PTGS2ALDH1A1TDP1CYP3A4PDK1
SCHEMBL8826652 0.80 FBP1 (0.45) PTGS2ALDH1A1TDP1CYP3A4PDK1
SCHEMBL330195 0.80 PTGS2 (0.33) PTGS2FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1793 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11852647-B2 Method for predicting the rubber reinforcing effect of organic-inorganic composite for rubber reinforcement LG CHEM, LTD. 2023-12-26 US claimed
CN-110199187-B Method for predicting rubber reinforcing effect of organic-inorganic composite material for rubber reinforcement 株式会社LG化学 2022-02-11 CN claimed
EP-3534144-B1 METHOD FOR PREDICTING RUBBER REINFORCEMENT EFFECT OF ORGANIC-INORGANIC COMPOSITE FOR RUBBER REINFORCEMENT LG CHEMICAL LTD (KR) 2021-12-22 EP claimed
US-11059956-B2 Organic-inorganic composite for rubber reinforcement, method for preparing the same, and rubber composition for tires comprising the same LG CHEM, LTD. (KR) 2021-07-13 US claimed
CN-110191917-B Organic-inorganic composite material for rubber reinforcement, method for preparing the same, and rubber composition for tire comprising the same 株式会社LG化学 2021-05-25 CN claimed
EP-3533825-B1 ORGANIC-INORGANIC COMPOSITE FOR REINFORCING RUBBER, PREPARATION METHOD THEREFOR, AND TIRE RUBBER COMPOSITION COMPRISING SAME LG CHEMICAL LTD (KR) 2020-10-21 EP claimed
CN-107108908-B Method for producing rubber composition for tire, and tire 住友橡胶工业株式会社 2020-05-15 CN claimed
US-20200131341-A1 Organic-Inorganic Composite for Rubber Reinforcement, Method for Preparing the Same, and Rubber Composition for Tires Comprising the Same LG CHEM, LTD. (KR) 2020-04-30 US claimed
US-20190310176-A1 Method for Predicting the Rubber Reinforcing Effect of Organic-Inorganic Composite for Rubber Reinforcement LG CHEM, LTD. (KR) 2019-10-10 US claimed
EP-3533825-A1 ORGANIC-INORGANIC COMPOSITE FOR REINFORCING RUBBER, PREPARATION METHOD THEREFOR, AND TIRE RUBBER COMPOSITION COMPRISING SAME LG Chem, Ltd. (KR) 2019-09-04 EP claimed
EP-3534144-A2 METHOD FOR PREDICTING RUBBER REINFORCEMENT EFFECT OF ORGANIC-INORGANIC COMPOSITE FOR RUBBER REINFORCEMENT LG Chem, Ltd. (KR) 2019-09-04 EP claimed
US-10369843-B2 Production method of rubber composition for tire and tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-08-06 US claimed
EP-3196233-B1 METHOD FOR PRODUCING RUBBER COMPOSITION FOR TIRE, AND TIRE SUMITOMO RUBBER IND (JP) 2019-07-24 EP claimed
EP-4438340-B1 TIRE WITH IMPROVED RUBBER COMPOUND BRIDGESTONE EUROPE NV SA (BE) 2026-05-27 EP disclosed
US-12630696-B2 Rubber composition, and tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-05-19 US disclosed
US-20260132240-A1 LINEAR BLOCK COPOLYMER AND CURABLE THERMOSETTING COMPOSITION COMPRISING THE LINEAR BLOCK COPOLYMER SHPP GLOBAL TECH B V (NL) 2026-05-14 US disclosed
EP-0894825-A1 DIENE POLYMER COMPOSITION, PROCESS FOR THE PREPARATION OF THE SAME, AND RUBBER COMPOSITION CONTAINING THE SAME NIPPON ZEON CO., LTD. (JP) 1999-02-03 EP disclosed
EP-0819731-A1 DIENE RUBBER COMPOSITION NIPPON ZEON CO., LTD. (JP) 1998-01-21 EP disclosed
EP-0818478-A1 STYRENE-ISOPRENE-BUTADIENE COPOLYMER RUBBER AND PROCESS FOR THE PRODUCTION THEREOF NIPPON ZEON CO., LTD. (JP) 1998-01-14 EP disclosed
EP-0816424-A1 RUBBER COMPOSITION NIPPON ZEON CO., LTD. (JP) 1998-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630696-B2 Rubber composition, and tire THRB, RIF1, THRA PTGS2 2160/4885ALDH1A1 3448/4885TDP1 1832/4885
US-20260132240-A1 LINEAR BLOCK COPOLYMER AND CURABLE THERMOSETTING COMPOSITION COMPRISING THE LINEAR BLOCK COPOLYMER CBLB, UBE4A, PSMD14 PTGS2 1186/4885ALDH1A1 1440/4885TDP1 2354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.