SCHEMBL2899116

SCHEMBL2899116

Cc1cc(Oc2ccc3cc(O)ccc3c2)nc(Oc2ccc3cc(O)ccc3c2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 2/20 0.49
HPGD P15428 2/20 0.49
HSD17B10 Q99714 2/20 0.49
KMT2A Q03164 6/20 0.44
MEN1 O00255 5/20 0.44
ESR1 P03372 6/20 0.42
CYP1A2 P05177 1/20 0.41
NPC1 O15118 2/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
ESR2 Q92731 5/20 0.40
LMNA P02545 2/20 0.39
MAPT P10636 3/20 0.39
TSHR P16473 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
ATM Q13315 1/20 0.39
HAO1 Q9UJM8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2905883 0.87 HPGD (0.53) KDM4EALDH1A1HPGDHSD17B10KMT2A
SCHEMBL5690174 0.83 DRD1 (0.43) KDM4EALDH1A1HPGDHSD17B10KMT2A
SCHEMBL2906573 0.82 HPGD (0.49) KDM4EALDH1A1HPGDHSD17B10KMT2A
SCHEMBL2903652 0.81 F2 (0.49) KDM4EALDH1A1HPGDHSD17B10KMT2A
SCHEMBL2900905 0.81 ALDH1A1 (0.42) KDM4EALDH1A1HPGDHSD17B10KMT2A
SCHEMBL2898204 0.80 ALDH1A1 (0.51) KDM4EALDH1A1HPGDHSD17B10KMT2A
SCHEMBL2903830 0.80 HSD17B1 (0.47) KDM4EALDH1A1HPGDHSD17B10KMT2A
SCHEMBL2906030 0.79 MEN1 (0.45) KDM4EALDH1A1HPGDHSD17B10KMT2A
SCHEMBL2906403 0.79 F2 (0.49) KDM4EALDH1A1HPGDHSD17B10KMT2A
SCHEMBL18862303 0.79 ALDH1A1 (0.48) KDM4EALDH1A1HPGDHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1636209-B1 EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT SUMITOMO CHEMICAL CO (JP) 2010-08-11 EP disclosed
US-7279574-B2 Epoxy compound and cured epoxy resin product SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-09 US disclosed
US-20060159929-A1 Epoxy compound and cured epoxy resin product HITACHI, LTD. (JP) 2006-07-20 US disclosed