SCHEMBL2905883

SCHEMBL2905883

Cc1cc(Oc2ccc(O)cc2)nc(Oc2ccc(O)cc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.53
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 1/20 0.53
HSD17B10 Q99714 1/20 0.53
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
LTA4H P09960 5/20 0.48
NR1H2 P55055 1/20 0.48
BAX Q07812 1/20 0.48
LMNA P02545 3/20 0.45
MAPT P10636 3/20 0.45
TSHR P16473 3/20 0.45
NPSR1 Q6W5P4 2/20 0.45
NPC1 O15118 1/20 0.45
L3MBTL1 Q9Y468 3/20 0.44
MAPK1 P28482 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2906573 0.94 HPGD (0.49) HPGDKDM4EALDH1A1HSD17B10MEN1
SCHEMBL2899116 0.87 KDM4E (0.49) HPGDKDM4EALDH1A1HSD17B10MEN1
SCHEMBL5686902 0.79 DRD1 (0.50) HPGDKDM4EALDH1A1HSD17B10MEN1
SCHEMBL5634255 0.79 MEN1 (0.50) HPGDKDM4EALDH1A1HSD17B10MEN1
SCHEMBL2906444 0.78 ALDH1A1 (0.58) HPGDKDM4EALDH1A1HSD17B10MEN1
SCHEMBL2898802 0.77 LTA4H (0.60) HPGDKDM4EALDH1A1HSD17B10MEN1
SCHEMBL10874484 0.77 ALDH1A1 (0.65) ALDH1A1MEN1KMT2AESR1ESR2
SCHEMBL2901468 0.75 ESR2 (0.45) HPGDKDM4EALDH1A1HSD17B10MEN1
SCHEMBL2898728 0.75 MEN1 (0.54) HPGDKDM4EALDH1A1HSD17B10MEN1
SCHEMBL2906590 0.74 ALDH1A1 (0.54) HPGDKDM4EALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1636209-B1 EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT SUMITOMO CHEMICAL CO (JP) 2010-08-11 EP disclosed
US-7279574-B2 Epoxy compound and cured epoxy resin product SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-09 US disclosed
US-20060159929-A1 Epoxy compound and cured epoxy resin product HITACHI, LTD. (JP) 2006-07-20 US disclosed