SCHEMBL2906573

SCHEMBL2906573

Cc1cc(Oc2ccc(-c3ccc(O)cc3)cc2)nc(Oc2ccc(-c3ccc(O)cc3)cc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.49
HSD17B10 Q99714 2/20 0.49
KDM4E B2RXH2 1/20 0.49
ALDH1A1 P00352 1/20 0.49
ESR2 Q92731 4/20 0.47
ESR1 P03372 4/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
LTA4H P09960 2/20 0.44
NR1H2 P55055 1/20 0.44
BAX Q07812 1/20 0.44
ABL1 P00519 1/20 0.43
ABCB1 P08183 1/20 0.43
BCR P11274 1/20 0.43
MAPT P10636 3/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
MAPK1 P28482 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2905883 0.94 HPGD (0.53) HPGDHSD17B10KDM4EALDH1A1ESR2
SCHEMBL2899116 0.82 KDM4E (0.49) HPGDHSD17B10KDM4EALDH1A1ESR2
SCHEMBL2901468 0.81 ESR2 (0.45) HPGDHSD17B10KDM4EALDH1A1ESR2
SCHEMBL2906590 0.80 ALDH1A1 (0.54) HPGDHSD17B10KDM4EALDH1A1ESR2
SCHEMBL2905330 0.79 LTA4H (0.54) HPGDHSD17B10ALDH1A1ESR2ESR1
SCHEMBL2903641 0.79 LTA4H (0.54) HPGDHSD17B10ALDH1A1ESR2ESR1
SCHEMBL2904931 0.78 ESR2 (0.48) ALDH1A1ESR2ESR1MEN1KMT2A
SCHEMBL14311177 0.77 ESR2 (0.64) KDM4EALDH1A1ESR2ESR1MEN1
SCHEMBL15681790 0.77 ESR2 (0.64) KDM4EALDH1A1ESR2ESR1MEN1
SCHEMBL10035479 0.77 ESR2 (0.64) KDM4EALDH1A1ESR2ESR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1636209-B1 EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT SUMITOMO CHEMICAL CO (JP) 2010-08-11 EP disclosed
US-7279574-B2 Epoxy compound and cured epoxy resin product SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-09 US disclosed
US-20060159929-A1 Epoxy compound and cured epoxy resin product HITACHI, LTD. (JP) 2006-07-20 US disclosed
EP-1636209-A1 EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT Sumitomo Chemical Company, Limited (JP) 2006-03-22 EP disclosed
WO-2004113327-A1 EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-29 WO disclosed