Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 3/20 | 0.38 |
| ▸ | TLR2 | O60603 | 3/20 | 0.38 |
| ▸ | FBP1 | P09467 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30320138 | 0.75 | FBP1 (0.49) | TLR4TLR2FBP1MAPTHSP90AA1 | |
| SCHEMBL25607531 | 0.75 | FBP1 (0.49) | TLR4TLR2FBP1MAPTHSP90AA1 | |
| SCHEMBL20815627 | 0.70 | L3MBTL1 (0.47) | L3MBTL1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL25607532 | 0.70 | ALDH1A1 (0.51) | L3MBTL1KMT2AMEN1RAB9AFBP1 | |
| SCHEMBL25213136 | 0.69 | TLR4 (0.33) | L3MBTL1KMT2AMEN1TLR4TLR2 | |
| SCHEMBL28994122 | 0.67 | FBP1 (0.38) | L3MBTL1KMT2AMEN1TLR4TLR2 | |
| SCHEMBL17708625 | 0.67 | FBP1 (0.47) | FBP1MAPTHSP90AA1RXRAVCP | |
| SCHEMBL17708627 | 0.67 | FBP1 (0.47) | FBP1MAPTHSP90AA1RXRAVCP | |
| SCHEMBL25607559 | 0.66 | ALDH1A1 (0.39) | RAB9ATLR4TLR2FBP1MAPT | |
| SCHEMBL27830114 | 0.65 | POLB (0.47) | L3MBTL1KMT2AMEN1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867553-A | Diaminopyrazolo [1,5-a ] pyrimidine-6-carbonitrile compounds as adenosine 2A receptor and adenosine 2B receptor antagonists | 巴格沃克斯研究有限公司 | 2023-03-28 | — | — | CN | disclosed |