Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 10/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | VCP | P55072 | 3/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25607531 | 1.00 | FBP1 (0.49) | FBP1PRMT1VCPRXRAHSP90AA1 | |
| SCHEMBL25607532 | 0.78 | ALDH1A1 (0.51) | FBP1PRMT1VCPRXRAHSP90AA1 | |
| SCHEMBL17708625 | 0.78 | FBP1 (0.47) | FBP1VCPRXRAHSP90AA1MAPT | |
| SCHEMBL17708627 | 0.78 | FBP1 (0.47) | FBP1VCPRXRAHSP90AA1MAPT | |
| SCHEMBL28994099 | 0.75 | L3MBTL1 (0.39) | FBP1VCPRXRAHSP90AA1TLR4 | |
| SCHEMBL25819348 | 0.75 | IDH1 (0.43) | ALDH1A1LMNAMAPK1TGFBR1IDH1 | |
| SCHEMBL22578205 | 0.74 | IDH1 (0.41) | ALDH1A1SMN1; SMN2TGFBR1IDH1NPSR1 | |
| SCHEMBL22578203 | 0.74 | IDH1 (0.41) | ALDH1A1SMN1; SMN2TGFBR1IDH1NPSR1 | |
| SCHEMBL9000609 | 0.74 | TGFBR1 (0.44) | ALDH1A1SMN1; SMN2TGFBR1IDH1NPSR1 | |
| SCHEMBL506568 | 0.73 | IDH1 (0.47) | TLR2ALDH1A1MAPTTGFBR1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867553-A | Diaminopyrazolo [1,5-a ] pyrimidine-6-carbonitrile compounds as adenosine 2A receptor and adenosine 2B receptor antagonists | 巴格沃克斯研究有限公司 | 2023-03-28 | — | — | CN | disclosed |