Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | METAP2 | P50579 | 7/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29191234 | 0.91 | METAP2 (0.56) | LMNAHTTMETAP2PTGDR2KCNA5 | |
| SCHEMBL28996151 | 0.86 | METAP2 (0.62) | LMNAHTTMETAP2PTGDR2KCNA5 | |
| SCHEMBL28995936 | 0.83 | MCL1 (0.60) | LMNAHTTMETAP2CYP1A2CYP2C9 | |
| SCHEMBL14087834 | 0.82 | METAP2 (0.70) | LMNAHTTMETAP2PTGDR2CYP1A2 | |
| SCHEMBL13034765 | 0.80 | LMNA (0.60) | LMNAHTTMETAP2PTGDR2KCNA5 | |
| SCHEMBL13034766 | 0.80 | METAP2 (0.62) | LMNAHTTMETAP2PTGDR2CYP1A2 | |
| SCHEMBL28995990 | 0.79 | LMNA (0.67) | LMNAHTTMETAP2TP53MAPT | |
| SCHEMBL28995977 | 0.78 | HSD17B2 (0.58) | LMNAHTTMETAP2CYP1A2CYP2C9 | |
| SCHEMBL13034754 | 0.78 | FFAR4 (0.60) | LMNAHTTMETAP2PTGDR2CYP1A2 | |
| SCHEMBL14075202 | 0.77 | METAP2 (0.62) | LMNAHTTMETAP2PTGDR2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082269-B | 1,3, 4-Oxazoline compound containing trifluoromethyl quaternary carbon center and preparation method thereof | 盐城工学院 | 2024-06-21 | — | — | CN | disclosed |
| CN-116082269-A | 1,3, 4-oxazoline compound containing trifluoromethyl quaternary carbon center and preparation method thereof | 盐城工学院 | 2023-05-09 | — | — | CN | disclosed |