Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314105 | 0.84 | ASIC3 (0.67) | ASIC3HSP90AA1MEN1ALDH1A1LMNA | |
| SCHEMBL9151109 | 0.82 | ASIC3 (0.64) | ASIC3HSP90AA1MEN1ALDH1A1LMNA | |
| SCHEMBL9132100 | 0.82 | ASIC3 (0.64) | ASIC3HSP90AA1MEN1ALDH1A1LMNA | |
| SCHEMBL9132675 | 0.82 | ASIC3 (0.64) | ASIC3HSP90AA1MEN1ALDH1A1LMNA | |
| SCHEMBL20911220 | 0.81 | HSP90AA1 (0.44) | ASIC3HSP90AA1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30252597 | 0.81 | HSP90AA1 (0.44) | ASIC3HSP90AA1PIK3CDPIK3CAPIK3CB | |
| Dalfampridine SCHEMBL9979017 | 0.80 | MAPT (0.62) | ASIC3HSP90AA1MEN1ALDH1A1LMNA | |
| SCHEMBL902145 | 0.78 | KARS1 (0.44) | ASIC3HSP90AA1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL5321481 | 0.77 | NISCH (0.43) | HSP90AA1PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL20169521 | 0.77 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651358-B | 4-aminopyridine derivative, pharmaceutical composition, preparation method and application thereof | 上海迪诺医药科技有限公司 | 2023-04-07 | — | — | CN | disclosed |