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Propionic Acid

Propionic Acid

SCHEMBL28996320

CCC(=O)O.CCCCCCCCCCCCCC(CCO)c1ccc(OC(NC(C)C)C(C)O)cc1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GPR88 Q9GZN0 3/20 0.37
▸ MMP9 P14780 3/20 0.35
▸ MMP13 P45452 3/20 0.35
▸ MMP8 P22894 1/20 0.35
▸ POLB P06746 1/20 0.34
▸ MMP1 P03956 2/20 0.33
▸ ADAM17 P78536 2/20 0.33
▸ NR1I2 O75469 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ CTRC Q99895 1/20 0.32
▸ S1PR1 P21453 1/20 0.32
▸ S1PR3 Q99500 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28996459 0.84 SMN1; SMN2 (0.38) MMP9MMP13MMP8POLBMMP1
Propionic Acid SCHEMBL28996318 0.78 ADRB2 (0.49) LMNA
SCHEMBL9628819 0.70 PTGS2 (0.44) LMNA
SCHEMBL17868805 0.68 CSNK1E (0.44) NR1I2
SCHEMBL7642555 0.68 CSNK1E (0.44) NR1I2
SCHEMBL1555460 0.68 CSNK1E (0.44) NR1I2
SCHEMBL27294655 0.68 CSNK1E (0.44) NR1I2
SCHEMBL28996325 0.68 P2RY10 (0.48) S1PR1S1PR3
3-Methylbutanol SCHEMBL10956241 0.67 TP53 (0.46) NR1I2
SCHEMBL2307049 0.67 TRPA1 (0.44) POLBNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116036305-B Nanometer medicine and its prepn and application 广州国家实验室 2023-09-15 — — CN disclosed
CN-116036305-A Nanometer medicine and its prepn and application 广州国家实验室 2023-05-02 — — CN disclosed
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