Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | MMP13 | P45452 | 3/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL28996320 | 0.84 | GPR88 (0.37) | SMN1; SMN2POLBMMP9MMP13MMP1 | |
| SCHEMBL28996457 | 0.78 | ADRB2 (0.47) | LMNA | |
| SCHEMBL28996325 | 0.76 | P2RY10 (0.48) | — | |
| Hydrochloric Acid SCHEMBL10878734 | 0.70 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1HPGDRAB9ALMNA | |
| SCHEMBL27886819 | 0.69 | LTA4H (0.44) | SMN1; SMN2NAAAHTTNPC1RAB9A | |
| SCHEMBL28034758 | 0.69 | NAAA (0.54) | SMN1; SMN2MAPK1NAAAHTTPOLB | |
| SCHEMBL30327229 | 0.68 | NAAA (0.42) | NAAA | |
| SCHEMBL9628819 | 0.67 | PTGS2 (0.44) | LMNA | |
| SCHEMBL11570658 | 0.67 | NR1I2 (0.42) | SMN1; SMN2SLC2A1MMP9MMP13NPC1 | |
| SCHEMBL11569703 | 0.67 | NR1I2 (0.42) | SMN1; SMN2SLC2A1MMP9MMP13NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116036305-B | Nanometer medicine and its prepn and application | 广州国家实验室 | 2023-09-15 | — | — | CN | disclosed |
| CN-116036305-A | Nanometer medicine and its prepn and application | 广州国家实验室 | 2023-05-02 | — | — | CN | disclosed |