Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29241023 | 0.82 | KAT6A (0.34) | NFE2L2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28996381 | 0.80 | PTGS2 (0.35) | POLBPTGS1PTGS2NPC1RAB9A | |
| SCHEMBL30250386 | 0.75 | RIPK1 (0.33) | KAT6A | |
| SCHEMBL25316119 | 0.70 | NFE2L2 (0.39) | NFE2L2POLBGRM5F2RL3KDM4E | |
| SCHEMBL1278609 | 0.68 | NFE2L2 (0.40) | NFE2L2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL25193028 | 0.66 | CHRNB4 (0.37) | NFE2L2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31019973 | 0.66 | CHRNB4 (0.37) | NFE2L2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1580915 | 0.66 | LMNA (0.38) | NFE2L2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL25275117 | 0.65 | OXTR (0.38) | PTGS1PTGS2KDM4EALDH3A1 | |
| SCHEMBL31522099 | 0.65 | AVPR2 (0.40) | PTGS1PTGS2KDM4EALDH1A1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115884968-B | Novel acid secretion inhibitor and use thereof | 日东制药株式会社 | 2024-06-21 | — | — | CN | disclosed |
| CN-115884968-A | Novel acid secretion inhibitor and use thereof | 日东制药株式会社 | 2023-03-31 | — | — | CN | disclosed |