Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | KHK | P50053 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL2822777 | 0.98 | ALOX15 (0.47) | ALOX15MAPTALDH1A1MAPK1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL27403116 | 0.98 | ALOX15 (0.47) | ALOX15MAPTALDH1A1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL16043238 | 0.85 | MAPT (0.42) | ALOX15MAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8373357 | 0.82 | SLC16A3 (0.58) | ALOX15MAPTALDH1A1MAPK1KDM4E | |
| SCHEMBL10533803 | 0.80 | MAPT (0.71) | ALOX15MAPTHSD17B10RECQLSLC16A3 | |
| SCHEMBL13168765 | 0.79 | ALOX15 (0.41) | ALOX15MAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL5009531 | 0.78 | L3MBTL1 (0.45) | ALOX15ALDH1A1MAPK1L3MBTL1GLS | |
| SCHEMBL6090368 | 0.78 | GLS (0.66) | ALOX15MAPTALDH1A1L3MBTL1SLC9A1 | |
| SCHEMBL13131353 | 0.77 | REN (0.47) | ALOX15ALDH1A1L3MBTL1GLSKDM4E | |
| SCHEMBL25153639 | 0.77 | SLC9A1 (0.43) | MAPTALDH1A1L3MBTL1SLC9A1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11203589-B2 | Pyrimidine or pyridine compounds, preparation method therefor and pharmaceutical uses thereof | InventisBio Co., Ltd. (CN) | 2021-12-21 | — | — | US | disclosed |
| US-10179784-B2 | Pyrimidine or pyridine compounds, preparation method therefor and pharmaceutical uses thereof | INVENTISBIO SHANGHAI LTD. (CN) | 2019-01-15 | — | — | US | disclosed |
| US-20170355696-A1 | PYRIMIDINE OR PYRIDINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF | InventisBio Co., Ltd. (CN) | 2017-12-14 | — | — | US | disclosed |
| WO-2017040449-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-09 | — | — | WO | disclosed |
| US-20100286406-A1 | 1,3- DIALKYLBENZIMIDAZOLE HALOGENIDES EXHIBITING REGENERATIVE, ANTI-INFLAMMATORY, AND ANTIMICROBIAL ACTIVITY | STRADOMSKIY, BORIS VITALYEVICH (RU) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11203589-B2 | Pyrimidine or pyridine compounds, preparation method therefor and pharmaceutical uses thereof | EGFR, WEE1, TP53 | ALOX15 1320/4885MAPT 4373/4885ALDH1A1 1050/4885 |
| US-20100286406-A1 | 1,3- DIALKYLBENZIMIDAZOLE HALOGENIDES EXHIBITING REGENERATIVE, ANTI-INFLAMMATORY, AND ANTIMICROBIAL ACTIVITY | ALK, CFTR, FGFR1 | ALOX15 1240/4885MAPT 4854/4885ALDH1A1 118/4885 |
| US-20170355696-A1 | PYRIMIDINE OR PYRIDINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF | EGFR, WEE1, DPYD | ALOX15 1600/4885MAPT 4416/4885ALDH1A1 1411/4885 |
| US-10179784-B2 | Pyrimidine or pyridine compounds, preparation method therefor and pharmaceutical uses thereof | EGFR, WEE1, DPYD | ALOX15 1755/4885MAPT 4337/4885ALDH1A1 1173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.