SCHEMBL28996980

SCHEMBL28996980

N#CCC(N)c1ccccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 1/20 0.41
ALDH1A1 P00352 2/20 0.39
AOC3 Q16853 1/20 0.39
IDO1 P14902 2/20 0.38
TDO2 P48775 2/20 0.38
IDO2 Q6ZQW0 2/20 0.38
CYP3A4 P08684 2/20 0.37
CYP2D6 P10635 2/20 0.37
NFKB1 P19838 2/20 0.37
CYP1A2 P05177 1/20 0.37
PNMT P11086 1/20 0.37
LMNA P02545 2/20 0.36
GLA P06280 1/20 0.36
DPP4 P27487 1/20 0.36
ADRB2 P07550 2/20 0.35
ADRB1 P08588 2/20 0.35
CFD P00746 1/20 0.35
HIF1A Q16665 3/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28974289 0.85 PNMT (0.52) NISCHALDH1A1IDO1TDO2CYP3A4
Hydrochloric Acid SCHEMBL30209730 0.84 ALDH1A1 (0.53) NISCHALDH1A1IDO1TDO2IDO2
SCHEMBL13837017 0.82 CFD (0.55) ALDH1A1CYP3A4CYP2D6NFKB1CYP1A2
SCHEMBL27168749 0.80 ALDH1A1 (0.41) NISCHALDH1A1AOC3IDO1TDO2
SCHEMBL11076384 0.80 ALDH1A1 (0.41) NISCHALDH1A1AOC3IDO1TDO2
SCHEMBL29483408 0.80 ALDH1A1 (0.41) NISCHALDH1A1AOC3IDO1TDO2
SCHEMBL28655921 0.78 ALDH1A1 (0.40) NISCHALDH1A1AOC3IDO1TDO2
SCHEMBL10509388 0.78 NISCH (0.46) NISCHALDH1A1AOC3IDO1TDO2
SCHEMBL18704103 0.77 ADRB2 (0.50) NISCHALDH1A1AOC3IDO1TDO2
SCHEMBL17749161 0.77 ADRB2 (0.42) NISCHALDH1A1AOC3IDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115888686-A Cerium oxide @ carbon composite catalyst and synthesis method and application thereof 安徽师范大学 2023-04-04 CN disclosed