SCHEMBL28997141

SCHEMBL28997141

N#CCC1CCC(=O)N1c1ccc(Br)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.38
PTGER2 P43116 4/20 0.38
PTGER3 P43115 2/20 0.38
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
FAAH O00519 1/20 0.35
MGLL Q99685 1/20 0.35
HSP90AA1 P07900 1/20 0.33
ATM Q13315 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
AR P10275 1/20 0.33
PTGDR Q13258 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
TSHR P16473 1/20 0.33
CCR1 P32246 1/20 0.33
CCR2 P41597 1/20 0.33
ALDH1A1 P00352 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28997292 0.85 PTGER2 (0.40) RAB9APTGER2PTGER3MEN1KMT2A
SCHEMBL28997296 0.85 HTR7 (0.41) PTGER2PTGER3MEN1KMT2AMGLL
SCHEMBL28997274 0.85 AR (0.38) PTGER2PTGER3MEN1KMT2AMGLL
SCHEMBL28997140 0.85 PTGER2 (0.39) RAB9APTGER2PTGER3PTGDRALDH1A1
SCHEMBL28997153 0.83 MGLL (0.41) MEN1KMT2AMGLLHSP90AA1ATM
SCHEMBL30226199 0.83 MGLL (0.41) MEN1KMT2AMGLLHSP90AA1ATM
SCHEMBL28997150 0.81 KMT2A (0.41) MEN1KMT2AALDH1A1
SCHEMBL28997152 0.78 NOTUM (0.40) RAB9AMEN1KMT2AMGLLATM
SCHEMBL28997289 0.77 HSP90AA1 (0.35) RAB9APTGER2PTGER3KMT2AHSP90AA1
SCHEMBL28997293 0.76 KDM4E (0.42) MEN1KMT2AMGLLARTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894323-A Method for self-cyclizing cyanation of enaminoaniline compound 湖北工业大学 2023-04-04 CN disclosed