SCHEMBL28997153

SCHEMBL28997153

N#CCC1CCC(=O)N1c1cccc(Br)c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.41
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
RAF1 P04049 1/20 0.39
BRAF P15056 1/20 0.39
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
ALOX5 P09917 2/20 0.37
RXFP1 Q9HBX9 2/20 0.37
ALDH1A1 P00352 2/20 0.36
NPC1 O15118 1/20 0.36
AR P10275 1/20 0.33
HSP90AA1 P07900 1/20 0.33
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30226199 1.00 MGLL (0.41) MGLLATML3MBTL1RAF1BRAF
SCHEMBL28997293 0.85 KDM4E (0.42) MGLLMEN1KMT2AALOX5ALDH1A1
SCHEMBL30226142 0.85 KDM4E (0.42) MGLLMEN1KMT2AALOX5ALDH1A1
SCHEMBL30226089 0.84 FAAH (0.41) MGLLL3MBTL1MEN1KMT2AALOX5
SCHEMBL28997149 0.84 FAAH (0.41) MGLLL3MBTL1MEN1KMT2AALOX5
SCHEMBL28997141 0.83 RAB9A (0.38) MGLLATMMEN1KMT2ARXFP1
SCHEMBL28997140 0.83 PTGER2 (0.39) ALDH1A1NPC1
SCHEMBL28997152 0.77 NOTUM (0.40) MGLLATMMEN1KMT2AALDH1A1
SCHEMBL28997289 0.75 HSP90AA1 (0.35) L3MBTL1KMT2ANPC1ARHSP90AA1
SCHEMBL28997292 0.75 PTGER2 (0.40) MGLLMEN1KMT2AALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894323-A Method for self-cyclizing cyanation of enaminoaniline compound 湖北工业大学 2023-04-04 CN disclosed