SCHEMBL28997205

SCHEMBL28997205

N#CSc1ccc2c(c1)NC(C=O)CN2

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
POLB P06746 2/20 0.34
MAPT P10636 2/20 0.34
USP2 O75604 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
UBE2N P61088 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD17B10 Q99714 1/20 0.34
FTO Q9C0B1 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NISCH Q9Y2I1 1/20 0.34
CA2 P00918 1/20 0.30
CA5A P35218 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29036205 0.73 CHRNB2 (0.31) MAPTCYP1A2KMT2A
SCHEMBL6926769 0.70 CREBBP (0.34) MAPTCYP1A2KMT2A
SCHEMBL28997204 0.68 SMYD3 (0.38) ALDH1A1POLBMAPTUSP2CYP1A2
SCHEMBL30350112 0.68 SMYD3 (0.38) ALDH1A1POLBMAPTUSP2CYP1A2
SCHEMBL27437424 0.67 TDP1 (0.35) ALDH1A1MAPTCYP1A2KMT2AHSD17B10
SCHEMBL27740237 0.67 CMA1 (0.34) POLBCYP1A2CYP3A4CYP2D6BLM
Methylamine SCHEMBL27568812 0.66 BRD4 (0.35) MAPTCYP1A2KMT2A
SCHEMBL29036195 0.65 PDE3B (0.41) ALDH1A1MAPTCYP1A2MAPK1HSD17B10
Methylamine SCHEMBL27587572 0.65 KDM4E (0.33) MAPTKMT2ATDP1
SCHEMBL29007498 0.64 KDM4E (0.51) ALDH1A1MAPTUSP2CYP1A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115928111-A Method for electrochemically synthesizing 7-thiocyano-3,4-dihydroquinoxaline-2 (1H) -ketone compound 华南理工大学 2023-04-07 CN claimed
CN-115928111-A Method for electrochemically synthesizing 7-thiocyano-3,4-dihydroquinoxaline-2 (1H) -ketone compound 华南理工大学 2023-04-07 CN disclosed
CN-115928111-A Method for electrochemically synthesizing 7-thiocyano-3,4-dihydroquinoxaline-2 (1H) -ketone compound 华南理工大学 2023-04-07 CN disclosed
CN-115928111-A Method for electrochemically synthesizing 7-thiocyano-3,4-dihydroquinoxaline-2 (1H) -ketone compound 华南理工大学 2023-04-07 CN disclosed