Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2891401 | 0.88 | HTT (0.46) | HTTLMNASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL6094081 | 0.80 | HTT (0.53) | HTTLMNASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL1279045 | 0.79 | HTT (0.73) | HTTSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL2182266 | 0.77 | HTT (0.71) | HTTLMNASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL17964410 | 0.77 | LTA4H (0.53) | HTTLMNASMN1; SMN2ALDH1A1LTA4H | |
| SCHEMBL30277724 | 0.76 | KIF11 (0.49) | HTTLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9229255 | 0.76 | APLNR (0.63) | NPSR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8931146 | 0.76 | HIF1A (0.48) | HTTSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL8931145 | 0.75 | APLNR (0.61) | LMNASMN1; SMN2NPSR1ALDH1A1KDM4E | |
| SCHEMBL2901392 | 0.74 | MAOA (0.40) | HTTLMNASMN1; SMN2NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215101-A1 | CATIONIC TRANSITION METAL CATALYSTS | Kanata Chemical Technologies Inc. (CA) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009055912-A1 | CATIONIC TRANSITION METAL CATALYSTS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2009-05-07 | — | — | WO | disclosed |