Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.40 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31214258 | 0.86 | NNMT (0.42) | NNMTP4HA1MIFP4HTMKDM4E | |
| SCHEMBL29005254 | 0.77 | NNMT (0.40) | NNMT | |
| SCHEMBL28976769 | 0.75 | KDM4E (0.52) | P4HTMKDM4EALOX15TSHRACMSD | |
| SCHEMBL1544188 | 0.74 | NNMT (0.68) | NNMTP4HA1MIFP4HTMKDM4E | |
| SCHEMBL29005159 | 0.72 | SIRT6 (0.42) | P4HA1MIFP4HTMKDM4EALOX15 | |
| SCHEMBL698657 | 0.72 | KDM4E (0.52) | NNMTP4HA1MIFP4HTMKDM4E | |
| SCHEMBL28972379 | 0.71 | MAPT (0.54) | NNMTP4HA1MIFP4HTML3MBTL1 | |
| SCHEMBL29127599 | 0.71 | — | — | |
| SCHEMBL29106396 | 0.71 | MEN1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL28979555 | 0.71 | BCAT2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134018-A | 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-116056697-A | 2-oxo-oxazolidine-5-carboxamides as NAV1.8 inhibitors | 默沙东有限责任公司 | 2023-05-02 | — | — | CN | disclosed |