Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29005279 | 0.78 | SIRT6 (0.39) | MLYCD | |
| SCHEMBL29005296 | 0.77 | NNMT (0.40) | NNMT | |
| SCHEMBL29005252 | 0.74 | L3MBTL1 (0.43) | NNMTMLYCD | |
| SCHEMBL30342225 | 0.74 | L3MBTL1 (0.43) | NNMTMLYCD | |
| SCHEMBL24724207 | 0.72 | MLYCD (0.37) | NNMTMLYCDTRPM8 | |
| SCHEMBL30003812 | 0.72 | MLYCD (0.37) | NNMTMLYCDTRPM8 | |
| SCHEMBL2541582 | 0.71 | PKM (0.39) | NNMTMLYCDTRPM8 | |
| SCHEMBL15142310 | 0.69 | NNMT (0.61) | NNMT | |
| SCHEMBL29162132 | 0.68 | TRPM8 (0.38) | MLYCDTRPM8 | |
| SCHEMBL29106396 | 0.67 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134018-A | 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-116056697-A | 2-oxo-oxazolidine-5-carboxamides as NAV1.8 inhibitors | 默沙东有限责任公司 | 2023-05-02 | — | — | CN | disclosed |