Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320692 | 0.93 | RAB9A (0.64) | RAB9ANPC1MAPTTDP1ALDH1A1 | |
| SCHEMBL27628173 | 0.91 | RAB9A (0.69) | RAB9ANPC1MAPTTDP1ALDH1A1 | |
| SCHEMBL8269548 | 0.89 | HSD11B1 (0.64) | RAB9ANPC1TDP1ALDH1A1HSD11B1 | |
| SCHEMBL7868068 | 0.87 | RAB9A (0.56) | RAB9ANPC1MAPTTDP1ALDH1A1 | |
| SCHEMBL1515775 | 0.86 | MEN1 (0.61) | RAB9ANPC1TDP1GPR52HSD11B1 | |
| SCHEMBL30416831 | 0.84 | ALDH1A1 (0.69) | RAB9ANPC1MAPTTDP1ALDH1A1 | |
| SCHEMBL4722288 | 0.84 | ALDH1A1 (0.69) | RAB9ANPC1MAPTTDP1ALDH1A1 | |
| SCHEMBL14306005 | 0.83 | ALDH1A1 (0.60) | RAB9ANPC1MAPTTDP1ALDH1A1 | |
| SCHEMBL7195774 | 0.82 | MAPT (0.56) | MAPTTDP1ALDH1A1HSD11B1CES2 | |
| SCHEMBL1304210 | 0.82 | NPC1 (1.00) | RAB9ANPC1MAPTALDH1A1GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478395-B | A kind of method of iridium catalyzed synthesizing alpha-alkyl ketone | 南京理工大学 | 2019-06-25 | — | — | CN | disclosed |
| CN-106478395-A | A kind of method of iridium catalyzed synthesizing alpha-alkyl ketone | 南京理工大学 | 2017-03-08 | — | — | CN | disclosed |
| CN-105906543-A | Novel synthesis method of multifunctional pyrrole | 常州大学 | 2016-08-31 | — | — | CN | disclosed |
| US-6653508-B2 | Use treating various medical conditions, including pain | GRUENENTHAL GMBH (DE) | 2003-11-25 | — | — | US | disclosed |
| US-20020161262-A1 | 3-Amino-2-benzyl-1-phenylpropane derivatives | GRUENTENTHAL GMBH (DE) | 2002-10-31 | — | — | US | disclosed |
| EP-1196373-A1 | 3-AMINO-2-BENZYL-1-PHENYL-PROPANE DERIVATIVES | Grünenthal GmbH (DE) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001005743-A1 | 3-AMINO-2-BENZYL-1-PHENYL-PROPANE DERIVATIVES | Grünenthal GmbH (DE) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161262-A1 | 3-Amino-2-benzyl-1-phenylpropane derivatives | PYGL, CYP11B2, GOT2 | RAB9A 1573/4885NPC1 11/4885MAPT 1038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.