Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2900809 | 0.81 | L3MBTL1 (0.50) | LMNAALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL7945642 | 0.75 | S1PR4 (0.38) | — | |
| SCHEMBL2902967 | 0.74 | HTT (0.53) | HTTLMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL2900123 | 0.74 | ALDH1A1 (0.40) | LMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL2897754 | 0.72 | MAP4K4 (0.43) | — | |
| SCHEMBL2894972 | 0.71 | MEN1 (0.52) | HTTLMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL2752900 | 0.70 | ALDH1A1 (0.41) | HTTALDH1A1 | |
| SCHEMBL2894735 | 0.70 | MAP4K4 (0.44) | HTTLMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7954135 | 0.70 | GAA (0.43) | LMNASMN1; SMN2GAA | |
| SCHEMBL2900607 | 0.69 | POLB (0.41) | HTTLMNAALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | HTT 2101/4885LMNA 2262/4885ALDH1A1 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.