Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2894972 | 0.82 | MEN1 (0.52) | MAP4K4KMT2AKDM4EMAPT | |
| SCHEMBL19211769 | 0.81 | CHRNA3 (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL19211767 | 0.81 | MEN1 (0.36) | KMT2AKDM4ECHRNB2CHRNA4 | |
| SCHEMBL19211880 | 0.79 | KDM4E (0.41) | KMT2AKDM4ECHRNB2CHRNA4MAPT | |
| SCHEMBL2903058 | 0.79 | MEN1 (0.44) | MAP4K4KMT2AKDM4EMAPT | |
| SCHEMBL1446447 | 0.78 | MAP4K4 (0.41) | MAP4K4GRM5KMT2ATGFBR1CHRNB2 | |
| SCHEMBL1711885 | 0.78 | LMNA (0.49) | MAP4K4KMT2ACHRNB2CHRNA4MAPT | |
| SCHEMBL2900123 | 0.77 | ALDH1A1 (0.40) | KMT2AKDM4EMAPT | |
| SCHEMBL8736739 | 0.75 | KDM4E (0.50) | MAP4K4GRM5HTR2CKMT2AKDM4E | |
| SCHEMBL1712271 | 0.75 | MEN1 (0.50) | KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | MAP4K4 2930/4885GRM5 455/4885HTR2C 3115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.