Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009185 | 0.88 | ALDH1A1 (0.50) | KDM4EALDH1A1GAATP53KMT2A | |
| SCHEMBL29009154 | 0.87 | GAA (0.42) | LMNAKDM4EALDH1A1GLAGAA | |
| SCHEMBL29009205 | 0.87 | LMNA (0.48) | LMNAHPGDKDM4EALDH1A1GLA | |
| SCHEMBL29009201 | 0.75 | ALDH1A1 (0.49) | KDM4EALDH1A1GAATP53KMT2A | |
| SCHEMBL29009182 | 0.75 | CA12 (0.43) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL29009203 | 0.72 | MEN1 (0.43) | LMNAKDM4EALDH1A1GLAGAA | |
| SCHEMBL4238229 | 0.72 | KMT2A (0.51) | LMNAALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL832583 | 0.70 | HPGD (0.41) | LMNAHPGDKDM4EALDH1A1GLA | |
| SCHEMBL4241297 | 0.70 | NR0B1 (0.46) | LMNAHPGDKDM4EALDH1A1GLA | |
| SCHEMBL1703036 | 0.68 | HPGD (0.45) | LMNAHPGDKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217458-A | 2-carbonyl-5-phenylpyrrole compound, preparation method, application and derivative thereof, and pharmaceutical composition | 湖北民族大学 | 2023-06-06 | — | — | CN | disclosed |