Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009205 | 0.88 | LMNA (0.48) | TP53ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL29009201 | 0.88 | ALDH1A1 (0.49) | CA1CA2TP53ALDH1A1MEN1 | |
| SCHEMBL29009203 | 0.88 | MEN1 (0.43) | TP53ALDH1A1ALOX15MEN1KMT2A | |
| SCHEMBL4238229 | 0.88 | KMT2A (0.51) | ALDH1A1ALOX15MEN1KMT2ATSHR | |
| SCHEMBL29009185 | 0.75 | ALDH1A1 (0.50) | CA1CA2TP53ALDH1A1MEN1 | |
| SCHEMBL29009158 | 0.75 | LMNA (0.49) | TP53ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL29009154 | 0.74 | GAA (0.42) | TP53ALDH1A1ALOX15MEN1KMT2A | |
| SCHEMBL19736005 | 0.72 | DHFR (0.52) | CA1CA2ALDH1A1TSHRKDM4E | |
| SCHEMBL10112947 | 0.71 | HSD17B10 (0.69) | TP53ALDH1A1HSD17B10ALOX15MAPK1 | |
| SCHEMBL4246931 | 0.69 | ALOX15 (0.46) | CA2ALDH1A1HSD17B10ALOX15MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217458-A | 2-carbonyl-5-phenylpyrrole compound, preparation method, application and derivative thereof, and pharmaceutical composition | 湖北民族大学 | 2023-06-06 | — | — | CN | disclosed |