Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009185 | 0.87 | ALDH1A1 (0.50) | GAATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL29009158 | 0.87 | LMNA (0.49) | GAATP53SLC6A3MEN1KMT2A | |
| SCHEMBL29009203 | 0.86 | MEN1 (0.43) | GAARXFP1MAPTTP53SLC6A4 | |
| SCHEMBL29009201 | 0.74 | ALDH1A1 (0.49) | GAATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL29009205 | 0.74 | LMNA (0.48) | GAATP53SLC6A3MEN1KMT2A | |
| SCHEMBL29009182 | 0.74 | CA12 (0.43) | GAATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL21250244 | 0.72 | HTR7 (0.45) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL21247502 | 0.72 | SLC6A4 (0.44) | GAAMAPTTP53SLC6A4SLC6A3 | |
| SCHEMBL29009151 | 0.71 | ALDH1A1 (0.45) | RXFP1SLC6A4SLC6A3TDP1MEN1 | |
| SCHEMBL4238229 | 0.71 | KMT2A (0.51) | MEN1KMT2AALDH1A1ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217458-A | 2-carbonyl-5-phenylpyrrole compound, preparation method, application and derivative thereof, and pharmaceutical composition | 湖北民族大学 | 2023-06-06 | — | — | CN | disclosed |