Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009197 | 0.87 | CHRNA7 (0.52) | CHRNA7KMT2AMAOAMAOBMMP1 | |
| SCHEMBL30466251 | 0.83 | CHRNA7 (0.48) | CHRNA7RAB9ANPC1POLBALDH1A1 | |
| SCHEMBL29009173 | 0.82 | NT5E (0.39) | CHRNA7L3MBTL1MAOAMAOBALDH1A1 | |
| SCHEMBL29009165 | 0.78 | KDM4E (0.50) | CHRNA7KMT2AMAOAMAOBMAPK1 | |
| SCHEMBL29009150 | 0.73 | SLC6A3 (0.46) | — | |
| SCHEMBL18106723 | 0.69 | ALDH1A1 (0.46) | L3MBTL1KMT2AMAOAMAOBEDNRB | |
| SCHEMBL18609335 | 0.69 | ALDH1A1 (0.46) | L3MBTL1KMT2AMAOAMAOBEDNRB | |
| SCHEMBL11478762 | 0.69 | L3MBTL1 (0.71) | L3MBTL1KMT2AMEN1ALDH1A1CA1 | |
| SCHEMBL18578796 | 0.69 | ALDH1A1 (0.46) | L3MBTL1KMT2AMAOAMAOBEDNRB | |
| SCHEMBL18106570 | 0.69 | ALDH1A1 (0.46) | L3MBTL1KMT2AMAOAMAOBEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217458-A | 2-carbonyl-5-phenylpyrrole compound, preparation method, application and derivative thereof, and pharmaceutical composition | 湖北民族大学 | 2023-06-06 | — | — | CN | disclosed |