Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009150 | 0.84 | SLC6A3 (0.46) | — | |
| SCHEMBL29009161 | 0.82 | CHRNA7 (0.53) | CHRNA7MAOAMAOBALDH1A1L3MBTL1 | |
| SCHEMBL29009165 | 0.75 | KDM4E (0.50) | CHRNA7MAOAMAOBCACNA1HKDM4E | |
| SCHEMBL29009197 | 0.70 | CHRNA7 (0.52) | CHRNA7MAOAMAOB | |
| SCHEMBL3921853 | 0.67 | TP53 (0.42) | KDM4EALDH1A1HTT | |
| SCHEMBL11491669 | 0.67 | L3MBTL1 (0.49) | HTTL3MBTL1 | |
| SCHEMBL30466251 | 0.66 | CHRNA7 (0.48) | CHRNA7ALDH1A1MAPTHTT | |
| SCHEMBL29009180 | 0.66 | ALDH1A1 (0.44) | KDM4EALDH1A1HTTL3MBTL1 | |
| SCHEMBL11621893 | 0.65 | MAOA (0.51) | NT5ECHRNA7MAOAMAOBALDH1A1 | |
| SCHEMBL11475285 | 0.65 | TDP1 (0.61) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217458-A | 2-carbonyl-5-phenylpyrrole compound, preparation method, application and derivative thereof, and pharmaceutical composition | 湖北民族大学 | 2023-06-06 | — | — | CN | disclosed |