Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | FPR2 | P25090 | 3/20 | 0.49 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.49 |
| ▸ | FPR1 | P21462 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30466251 | 0.94 | CHRNA7 (0.48) | MAPTALDH1A1CHRNA7POLBUSP2 | |
| SCHEMBL29009197 | 0.80 | CHRNA7 (0.52) | KMT2ACHRNA7MAOAMAOB | |
| SCHEMBL29009150 | 0.80 | SLC6A3 (0.46) | — | |
| SCHEMBL29009161 | 0.78 | CHRNA7 (0.53) | GAAMEN1KMT2AALDH1A1CHRNA7 | |
| SCHEMBL29009181 | 0.76 | FPR2 (0.53) | KDM4ELMNAGAAFPR2CACNA1H | |
| SCHEMBL29009173 | 0.75 | NT5E (0.39) | KDM4ECACNA1HMAPTALDH1A1CHRNA7 | |
| SCHEMBL29009174 | 0.72 | KDM4E (0.52) | KDM4ELMNAGAAFPR2FPR1 | |
| SCHEMBL1099077 | 0.70 | P2RX7 (0.66) | KDM4ELMNAGAAFPR2CACNA1H | |
| SCHEMBL19547770 | 0.70 | FPR2 (0.76) | FPR2FPR1 | |
| SCHEMBL18106517 | 0.70 | FPR2 (0.76) | FPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217458-A | 2-carbonyl-5-phenylpyrrole compound, preparation method, application and derivative thereof, and pharmaceutical composition | 湖北民族大学 | 2023-06-06 | — | — | CN | disclosed |