Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | FPR2 | P25090 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | FPR1 | P21462 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30466249 | 0.94 | RAB9A (0.49) | KDM4EMAPTTDP1HPGDPOLB | |
| SCHEMBL29009165 | 0.72 | KDM4E (0.50) | KDM4EMAPTALDH1A1TDP1LMNA | |
| SCHEMBL6295993 | 0.72 | NPC1 (0.83) | KDM4EALDH1A1HPGDLMNAPOLB | |
| Hydrochloric Acid SCHEMBL5797611 | 0.70 | NPC1 (0.81) | KDM4EALDH1A1HPGDLMNAPOLB | |
| SCHEMBL4921448 | 0.70 | RAB9A (0.81) | KDM4EMAPTLMNAFPR2TP53 | |
| SCHEMBL19547770 | 0.67 | FPR2 (0.76) | FPR2FPR1 | |
| SCHEMBL18106517 | 0.67 | FPR2 (0.76) | FPR2FPR1 | |
| SCHEMBL16785499 | 0.67 | FPR2 (0.76) | FPR2FPR1 | |
| SCHEMBL29434026 | 0.67 | FPR2 (0.76) | FPR2FPR1 | |
| SCHEMBL15709144 | 0.66 | TGM2 (0.63) | MAPTALDH1A1LMNAFPR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217458-A | 2-carbonyl-5-phenylpyrrole compound, preparation method, application and derivative thereof, and pharmaceutical composition | 湖北民族大学 | 2023-06-06 | — | — | CN | disclosed |