Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30466244 | 0.94 | MAP2K1 (0.51) | USP2MAPTMAP2K1RAB9ANPC1 | |
| SCHEMBL29009181 | 0.88 | FPR2 (0.53) | USP2MAPTMAP2K1MEN1KMT2A | |
| SCHEMBL29009179 | 0.78 | MMP1 (0.50) | MAPTBACE1MEN1KMT2ACYP2C19 | |
| SCHEMBL29009153 | 0.78 | CYP2D6 (0.44) | MEN1KMT2APOLBLMNA | |
| SCHEMBL10123277 | 0.75 | DEGS1 (0.70) | USP2MAPTGRIN2BRAB9ANPC1 | |
| SCHEMBL871979 | 0.75 | DEGS1 (0.70) | USP2MAPTGRIN2BRAB9ANPC1 | |
| SCHEMBL4242864 | 0.72 | NPC1 (0.50) | USP2MAPTGRIN2BRAB9ANPC1 | |
| SCHEMBL29009157 | 0.71 | RAB9A (0.55) | USP2MAPTRAB9ANPC1MEN1 | |
| SCHEMBL7726470 | 0.69 | MAPK1 (0.61) | MAP2K1RAB9ANPC1POLB | |
| SCHEMBL30466251 | 0.68 | CHRNA7 (0.48) | USP2MAPTMAP2K1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217458-A | 2-carbonyl-5-phenylpyrrole compound, preparation method, application and derivative thereof, and pharmaceutical composition | 湖北民族大学 | 2023-06-06 | — | — | CN | disclosed |